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Technology

RAPHAS DEN Technology

What is Raphas' DEN Technology?

Unlike conventional methods that involve applying materials to metal molds, heating, and UV irradiation to dry and form needles, Raphas' patented DEN (Droplet Extension) technology is an advanced process that manufactures microneedles at room temperature by utilizing the inherent viscosity of the raw ingredients and controlled airflow. Conventional techniques require materials to be heated in metal molds and then detached, making it difficult to incorporate heat- or UV-sensitive ingredients and limiting the ability to adjust needle shapes. In contrast, the DEN process boasts the distinct advantage of freely allowing the inclusion of sensitive ingredients and offering unparalleled flexibility in designing needle configurations.

Thanks to these technical advantages of the DEN process, brands can significantly broaden their formulation capabilities, bringing more innovative formulas and enhanced functionalities to their products. Moving beyond a mere difference in manufacturing methods, DEN technology is Raphas' exclusive core competency that expands the potential of microneedle products to entirely new dimensions.

DEN manufacturing process comparison
Key Benefits of DEN
  • Manufactured within 5 Minutes
  • Room Temperature Manufacturing (Stable formulation of highly sensitive ingredients such as vitamins and retinol)
  • Precise Dosage Loading
  • 51 Related Patents Held

Penetration Capability by Microneedle Length

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250μm

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350μm

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600μm

* Easily customizable microneedle lengths tailored to specific purposes and applications.